For its first outing since the pandemic, the art fair relocates Downtown and delivers a can’t-miss lineup of 75 emerging artists selected by an esteemed committee of art-world experts. Among this year’s exhibitors are Mary Lai, who draws from her background in graphic design to make colorful, punchy mixed-media works; Alex Selkowitz, whose paintings of urban settings hover between realistic and dream-like; and the painter Amanda Flowers, known for evocative depictions of Black mythology and euphoria on wood.